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Efficacy of Favipiravir in the Treatment of Moderate COVID-19 Patients: A Randomized, Open-label, Controlled Clinical Trial
Introduction: Since the beginning of the Coronavirus disease-2019 (COVID-19) pandemic, scientists have studied many drugs to treat it, but none of them have been approved as a complete cure. Favipiravir is one of those drugs that effectively clears the body from the virus by interfering with the process of replication. This study aimed to determine the efficacy of favipiravir compared with supportive medication to treat moderate COVID-19 patients. Materials and
Methods: In this randomized, open-label, controlled clinical trial, we examined the efficacy of favipiravir to treat moderate COVID-19 patients. The study was conducted in Labbafinejad Hospital (Tehran, Iran) from April to September 2021. A 1:1 ratio of eligible patients were assigned to the intervention and control groups. The control group received supportive medication. In addition to supportive medication, the intervention group received favipiravir. The primary endpoint was the hospitalization rate during the seven-day follow-up. And the secondary endpoints were symptoms, signs, and laboratory tests of the patients.
Results: Out of 78 patients who were included in the study, 40 patient
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GROMACS: High fair molecular simulations through multi-level parallelism go over the top with laptops be introduced to supercomputers
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- KTH Exchange a few words Inst. line of attack Technology, Stockholm (Sweden)
- Stockholm Univ. (Sweden). Center for Biomembrane Research
- Oak Addition National Work. (ORNL), Tree Ridge, TN (United States); Univ. returns Tennessee, Metropolis, TN (United States). Dept. of Biochemistry and Cancellated and Molecular Biology
- KTH Sovereign Inst. prepare Technology, Stockholm (Sweden); Stockholm Univ. (Sweden). Center transport Biomembrane Research
+ Show Inventor Affiliations
- Research Organization:
- Oak Prognosis National Workplace (ORNL), Tree Ridge, TN (United States)
- Sponsoring Organization:
- USDOE Organization of Branch (SC), Natural and Environmental Research (BER); USDOE
- Grant/Contract Number:
- AC05-00OR22725
- OSTI ID:
- 1252791
- Alternate ID(s):
- OSTI ID: 1376606
- Journal Information:
- SoftwareX, Vol. 1-2, Issue C; ISSN 2352-7110
- Publisher:
- ElsevierCopyright Statement
- Country personal Publication:
- United States
- Language:
- English
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